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HOWARU® Lpc-37®

HOWARU® Lpc-37®

HOWARU® Lacticaseibacillus paracasei LPC-37®

Image credits: © IFF, Finland, 2021 (FESEM imaging VTT)

HOWARU® Lacticaseibacillus paracasei​ Lpc-37® can be paired with other strains like NCFM®, Bi-07®, and Bl-04® in our HOWARU® Restore blend. Together, they support gut health, lessen the days of gut disruption and support overall digestive health.¹ Beyond digestion, Lpc-37® has been investigated for its impact on managing the psychological response to stress as HOWARU® Calm.² It’s not just about the gut—it’s about holistic wellbeing.

Product Information:
  • 126 scientific publications
  • 50+ clinical trials

Health Benefits:
Brain HealthBrain
Digestive HealthDigestive

Lpc-37® BLENDS

Learn more about IFF Health Sciences’ Lpc-37® blends.

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HOWARU® Calm

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HOWARU® GI Complete

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HOWARU® Restore

Lpc-37® CLINICAL STUDIES & PUBLICATIONS

Lpc-37® has been cited in more than 65 scientific publications, including more than 47 clinical trials. It has a long history of safe use, is well-suited for intestinal survival, and has strong adhesion to intestinal cell lines and pathogen inhibition.³⁻⁴

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Health Benefit Areas

Each strain’s health benefits are supported by recommended daily doses and peer-reviewed clinical studies.

Click on a Health Benefit to see more studies and learn more.

Supporting Daily Dose: 17B CFU Lpc-37®

Study Reference: Patterson E, et al. Neurobiol Stress. 2020;13:100277.

LEARN MORE

  1. Supporting Daily Dose: 2B CFU Lpc-37®

    Study Reference: Hemalatha R, et al. EJNF. 2014; 4(4):325-341.

  2. Supporting Daily Dose: 17B (equal parts) CFU Bl-04®, NCFM®, Bi-07®, Lpc-37®

    Study Reference: Ouwehand AC, et al. Vaccine. 2014;32(4):458-463.

  3. Supporting Daily Dose: 2.5B CFU NCFM®, 2.5B CFU Lpc-37®, 2.5B CFU Bl-04®, 2.5B CFU Bi-07®, 2B CFU HN019™

    Study Reference: Harris L, et al. J Clin Gastroenterol. 2022; 56(5):444-451

  4. Supporting Daily Dose: 10B CFU Total Bi-07®, Bl-04®, NCFM®, Lpc-37®

    Study Reference: van Zanten G, et al. Microorganisms. 2024; 12(4),796.

LEARN MORE

References: 1. Ouwehand AC, et al.;Vaccine. 2014​; 2. Patterson E, et al;.Neurobiol Stress. 2020​; 3. Ding WK, et al;,J Food Sci. 2007​; 4. Gibson GR, et al,; Br J Nutr. 2005.