HOWARU® Dophilus HOWARU® Dophilus Supports digestive health and gut comfort HOWARU® Dophilus features Lactobacillus acidophilus NCFM®, a human intestine isolate supported by numerous research publications, which was the first Lactobacillus acidophilus strain for which the complete genomic sequence has been obtained. Its clinical studies began in the 1970s and have since had more than 300 research papers published on it, confirming that this bacterium can help maintain a healthy intestinal environment. Product Information: Ingredients: HOWARU® Lactobacillus acidophilus NCFM® CFU: 1B CFU | Lactobacillus acidophilus NCFM® Health Benefits: Digestive ADVANTAGES Advantages of HOWARU® Dophilus Promotes overall gut comfort Helps relieve occasional constipation Helps support a healthy immune system SUPPORTS DIGESTIVE HEALTH AND GUT COMFORT L. acidophilus NCFM® was first isolated from a human source in the early 1970s. NCFM® has been investigated in more than 330 scientific studies, including more than 60 human clinical trials, as a single entity¹ and in combination with other probiotics and prebiotics. It has been studied alongside other strains as a component of the HOWARU® Restore Blend (NCFM®, Lpc-37®, Bi- 07®, Bl-04®) for digestive health and with Bi-07® for early life health.² ³ The subjects in these trials have ranged from infants to aging populations (from 6 months to over 65 years of age). It has a long history of safe use, is well suited for intestinal survival, and has strong adhesion to intestinal cell lines.⁴ ⁵ References: 1. Lyra et al., 2016; 2. Ouwehand et al., Vaccine. 2014; 3. Leyer et al., Pediatrics. 2009; 4. Andreasen et al., Br J Nutr. 2010; 5. Kleeman et al., J Dairy Sci. 1982.